AFP and hepatocellular carcinoma: AFP serum values pre-DAA treatment were commonly higher in HHC-O and HCC-R groups in comparison with the “without HCC” group (4.5 (IQR: 2.8–9.32) vs. 4.6 (IQR: 3–6.4) vs. 2.4 (IQR: 1.12–4.11), p < 0.001); however, AFP level was never markedly elevated.