EFEMP1 and metastatic malignant neoplasm in the lymph nodes: High EFEMP1 immunoexpression was significantly associated with high primary pathologic T (p < 0.001), lymph node metastasis (p = 0.001), high histological grade (p < 0.001), vascular invasion (p < 0.001), perineural invasion (p = 0.021) and high mitosis (p < 0.001).