Creatinine (mg/dL) was statistically significantly higher in hypertensive patients with AF, 1.04 ± 0.23, compared to those without AF, 0.91 ± 0.23 (p < 0.05) and transaminases (alanine aminotransferase (ALT), aspartate aminotransferase(AST)) showed statistically significantly higher values in hypertensive patients with AF, ALT (U/L) 32.77 ± 26.23, respectively AST (U/L) 29.22 ± 22.91, compared to patients without AF, ALT 26.49 ± 10.44, respectively AST 22.30 ± 6.97 (p < 0.05), without presenting pathological values in the two groups of patients. This evidence concerns the gene GPT and atrial fibrillation.