In a nutshell, these combined studies demonstrated that the administration of A. muciniphila protected against several cardiometabolic features (i.e., lowers body weight and fat-mass gain, hepatic steatosis, inflammation, cholesterol levels and atherosclerosis, improves insulin sensitivity and restores gut barrier function) [88,90,91,92,93,94,95,96]. Here, INS is linked to Hepatic steatosis.