In addition, PDLIM2 upregulation has been linked to a pattern of tumorigenesis suppression [10,11,12]; however, in malignant tumors, the chromosomal region containing the PDLIM2 gene is often destroyed, and high expression of PDLIM2 in cancer cell lines derived from metastatic cancer has been associated with the formation of malignant tumors [13,14]. Here, PDLIM2 is linked to metastatic malignant neoplasm.