To confirm whether PDLIM2 acts as an oncogene in human kidney cancer cells, we generated PDLIM2 knockdown stable human metastatic kidney cancer cell lines (shRNA-expressing Caki-1 cell lines; Sh_PDLIM2_01 and Sh_PDLIM2_02) using short hairpin RNA (shRNA) in Caki-1 cells (Figure 2B) and ACHN (Supplementary Figure S1). The gene discussed is PDLIM2; the disease is kidney cancer.