Pathways upregulated in PD and downregulated in its ODDCs presented high variability in the different cancers and included ribosome and translation-related pathways in BRCA; immune system-related pathways, such as signaling via NF-kB, inflammatory response, and interferon-gamma response, in LGCA; and epithelial-to-mesenchymal transition and extracellular matrix organization in PRCA. The gene discussed is NFKB1; the disease is Parkinson disease.