Several drugs indicated for cancer treatment presented negative correlations with AD profiles, including the aromatase inhibitor exemestane (r = −0.28) used for the treatment of BRCA, the progestin medication megestrol (r = −0.27), the alkylating agent thiotepa (r = −0.25), tretinoin (r = −0.25), and estradiol (r = −0.24). Here, CYP19A1 is linked to Alzheimer disease.