With respect to the HT-29 cancer cell line, treatment with KA39 increased PD-L1 expression by 313% and 304.9% when cells were treated at IC50 and the TGI concentration for 72 h, respectively (p < 0.01) (Figure 2B; Figures S6–S10; Tables S6–S10; Table 5). This evidence concerns the gene CD274 and cancer.