SLC26A4-AS1 lncRNA has been reported to promote NPTX1 transcriptional activity by recruiting nuclear factor kappa B 1 (NF-κB 1), which has an anti-angiogenic effect on glioma cells; the problem is that SLC26A4-AS1 expression is suppressed in glioma cells. Here, NPTX1 is linked to central nervous system cancer.