One other study remarks the impact of miR-374c-5p on apoptosis, controlling the proliferation, migration, epithelial-mesenchymal transition and apoptosis of human breast cancer cells, via repression of TATA box-binding protein associated 7 (TAF7) and expression of DEP domain containing 1 (DEPDC1), a transcriptional co-repressor involved in the promotion of carcinogenesis [166]. The gene discussed is DEPDC1; the disease is breast cancer.