Another very interesting approach of combining radiotherapy with CXCR4-targeted therapy was recently introduced by Séhédic et al. Their novel model of a nanocarrier-loaded combined lipophilic thiobenzoate complex of rhenium-188 in the core of a nanocapsule (LNC188Re) could potentially reach disseminated tumor cells which often escape therapeutic approaches [138]. This evidence concerns the gene CXCR4 and neoplasm.