In a tissue microarray containing 63 benign prostatic hyperplasia, 11 prostate cancer bone metastasis and 143 prostate cancers, AEG-1 expression was analysed by IHC which revealed that the expression was found to be higher in prostate cancer compared to benign prostatic hyperplasia (p = 0.037). The gene discussed is MTDH; the disease is prostate carcinoma.