METTL13 and acute myeloid leukemia: METTL13 deletion and eEF1AK55me2 loss dramatically reduce Ras-driven neoplastic growth in mouse models and in patient-derived xenografts from primary pancreatic and lung tumors [124], in line with findings in AML-193 and Kasumi-1 cells supporting the implication of eEF1A2K55me2 in acute myeloid leukemia [125].