GPT and diabetes mellitus: Fifty days of daily ALT therapy from 50 to 100 days of life modestly delayed the age of diabetes onset (control 141 ± 32 days vs. ALT 171 ± 38 days, p = 0.05; Figure 1A), but there were no differences in disease incidence when compared to control mice by the study end (control: 11/18; alagebrium: 15/20 mice, p = 0.5; Figure 1A).