The effects on blood pressure and thrombocytes function maintenance [78,80,81] are suggestive, BPC 157 may counteract induced hypertension and pro-thrombotic effect (L-NAME), and induced hypotension [78,81] and anti-thrombotic (L-arginine) effect [81], and finally, exert a vasomotor tone carried out through BPC 157 specific activation of Src-Caveolin-1-endothelial nitric oxide synthase (eNOS) pathway [47]. The gene discussed is NOS3; the disease is Hypertension.