TNFSF18 and neoplasm: Furthermore, platelets can transfer “normal” MHC I molecules onto the surface of tumor cells, impairing the “missing-self” recognition by NK cells or inducing the upregulation of NK cell inhibitory ligands, such as glucocorticoid-induced TNF-related ligands (GITRL), on tumor cells, leading to NK cell tolerance [91,92] (Figure 2A).