The aim of our study was to determine the allelic and genotypic frequencies of some single nucleotide polymorphisms (SNP) of DNA in 5 genes (adenosine triphosphate-binding cassette sub-family B member 1 (ABCB1)/multi drug reactivity 1 (MDR1) gene, genes coding for interleukin 10 (IL-10) and for tumor necrosis factor α (TNF-α)), which are targets of immunosuppressive therapies used in acute rejection in kidney transplantation and could therefore be involved in the pathogenesis of preeclampsia. The gene discussed is ABCB1; the disease is preeclampsia.