Further NAFLD complications may include IR (insulin resistance) (hepatic or system-wide level), increased production of inflammatory cytokines (IL-6 (Interleukin 6), C-reactive protein, TNF-α (tumour necrosis factor-alpha), and others), synthesis of procoagulant factors (factor VIII, endothelin, TGF-β (transforming growth factor-beta), fibrinogen, and others) and hepatokines, dysregulated glucose, and lipid metabolism [6,7]. The gene discussed is TNF; the disease is metabolic dysfunction-associated steatotic liver disease.