Moreover, 112 aberrantly expressed genes that influence ependymoma development were identified by Suarez-Merino et al. Their study includes the overexpression of oncogene Wnt family member 5A (WNT5A), tumor protein p63 (TP63), msh homeobox 1 (MSX1), insulin-like growth factor binding protein 2 (IGFBP2), chromobox 7 (CBX7), collagen type IV alpha 1 chain (COL4A1), WEE1 G2 checkpoint kinase (WEE1), leucine rich repeat neuronal 2 (LRRN2), angiogenesis factor vascular endothelial growth factor A (VEGFA), fibronectin 1 (FN1), and transcription factor ZIC1 [100]. Here, IGFBP2 is linked to ependymoma.