IGF2BP1 has an essential role in embryogenesis, tumorigenesis, and chemoresistance via serving as a post-transcriptional regulation by regulating the expression of some essential mRNA targets required for tumor cell growth and proliferation invasion as well as chemotherapy resistance [2,8,9,11,12,13,14,15,16,17,18,19], resulting in poor overall survival and metastasis in various types of cancers [10,20]. Here, IGF2BP1 is linked to cancer.