CD274 and neoplasm: The presence of intratumoral CD8+ TILs correlated significantly with PD-L1 expression by tumor cells: PD-L1 positivity was seen in 100% of the CD8high tumors, in 36% of the CD8low tumors and in 14% of the CD8− tumors (Table 2, Pearson’s chi-squared test, p = 0.000).