The mammary tumor associated RNA 25 (MaTAR25) long non-coding RNA (lncRNA) interacts with purine rich element binding protein B (PURB), and increases the expression of tensin 1, mRNA and protein levels [68], thereby contributing to cytoskeletal rearrangements that augment proliferation, migration, and invasion in breast cancer cells (Figure 4(Aiv)) [68]. The gene discussed is TNS1; the disease is breast cancer.