IL2 and neoplasm: These immunostimulatory effects were also observed in other research; for example, Liu et al., showed that oxymatrine promotes the maturation of dendritic cells [65], and Ye et al., found that it encourages CD8+ T cells isolated from tumor-bearing mice to secrete IFN-γ, TNF-α, and IL-2, which may be responsible for the synergistic anticancer effect of oxymatrine and cisplatin [66].