For example, TLR2 is associated with systemic lupus erythematosus (SLE) [78], sepsis [79], psoriasis [80]; TLR3 with sepsis [81]; TLR4 with SLE [82], sepsis [83], and psoriasis [80]; TLR5 with psoriasis [80]; TLR7 with SLE [84], stroke [85], and psoriasis [86]; and TLR9 is involved in SLE [87], sepsis [88] and psoriasis [89]. The gene discussed is TLR4; the disease is Stroke.