SDC1 and type 2 diabetes mellitus: The results demonstrated that T2D was not associated with significantly altered MMP-2 activity in the adventitia (1.04 ± 0.15 for T2D vs. 1.32 ± 0.38 ng/mL for the control, p = 0.90, Figure 2C) although plasma Sdc-1 levels were significantly lower in the T2D patient group compared with the control group (13.00 ± 1.22 for T2D vs. 19.41 ± 1.90 ng/mL for the control, p < 0.01, Figure 2D).