SDC1 and type 2 diabetes mellitus: Indeed, an increased expression of Sdc-1 was observed in the aortic adventitia of patients with T2D (0.78 ± 0.30 for T2D vs. 0.11 ± 0.03 procedure defined unit (p.d.u.)for the control, p < 0.001, Figure 2A,B).