Finally, in our functional analysis of aberrantly expressed AS exons in breast cancer cells and tissues (PACSIN2 exon 8, DIAPH1 exon 2, MARK3 exon 16, ADD3 exon 13, and MAP3K7 exon 12), we found that dysregulated cassette exons encode for IDRs. The gene discussed is MARK3; the disease is breast cancer.