The infiltration of TAMs to hypoxic tumor areas is due to various stimuli including Sema3A/Nrp1 signaling, VEGF, migratory stimulating factors such as colony-stimulating factor 1 (CSF1), CCL2, CCL5 as well as upregulation of TGFβ and M-CSFR [101,102,103]. Here, VEGFA is linked to neoplasm.