We clarified that 12 RBPs (RPS3, RBM22, EIF2S1, DHX8, RBM8A, UPF1, YBX1, SNRPE, SF3A1, U2AF1, SUPT6H, EIF3G) promoted tumor cell growth without expressional changes in all six cancer cell lines. Here, YBX1 is linked to cancer.