Among these, 12 RBPs (RPS3, RBM22, EIF2S1, DHX8, RBM8A, UPF1, YBX1, SNRPE, SF3A1, U2AF1, SUPT6H, EIF3G) promoted tumor cell growth without expressional changes in any cancer cell line (Table 2). The gene discussed is RBM22; the disease is neoplasm.