Among 12 the RBPs, 9 RBPs (RPS3, YBX1 (alternative name: YB-1), RBM8A (alternative name: RBM8(Y14)), RBM22, UPF1 (alternative name: RENT1), SNRPE, U2AF1 (alternative name: U2AF35), EIF3G (alternative name: eIF3), SUPT6H) comprised the cancer-associated network through the regulation of transcriptional factors that are key regulators of cancer cell growth, apoptosis or differentiation (Figure 6B and Table 4). This evidence concerns the gene U2AF1 and cancer.