GAS5 inhibits the progression of colorectal cancer through its direct interactions with the WW-domain of YAP (Yes1 Associated Transcriptional Regulator), thereby facilitating YAP translocation from the nucleus to the cytoplasm and promoting phosphorylation and ubiquitin-mediated degradation; this interaction takes place at 262–480 bp [41]. Here, YAP1 is linked to colorectal cancer.