ALDH1L1 and major depressive disorder: Supplementary Table S4 shows the genotyping call rate and p value for Hardy–Weinberg equilibrium for SNP rs114542799. To our knowledge, this is the first GWAS to discover the genome-wide significance level variant in the ALDH1L1 gene for probable female MDD. We confirmed that these GWAS results are novel for probable female MDD using the NHGRI-EBI GWAS Catalog [41].