PLAUR and systemic sclerosis: In the skin, the concomitant expression of endothelial and myofibroblast markers has been detected in ECs from SSc-affected dermal microvessels (Figure 1) and in both the bleomycin-induced and the urokinase-type plasminogen activator receptor (uPAR)-deficient mouse models of SSc [8,9,43,46,49].