Increased gene expression was observed in a cluster of chromatin and chromosome modulators (KAT2A and TERT), regulators of symmetric cell division (NUMB and PARD6A), osteogenic differentiation (FGFR1, IGF1, IGFR1, and VDR), self-renewal (SOX1), cancer stem cell markers (ALDH1A1 and CD24), stemness loss (PITCH1), migration and metastasis (IL8 and SNAI1) and pluripotency (NANOG and POU5F1). The gene discussed is NUMB; the disease is cancer.