CAAP1 and oral cavity squamous cell carcinoma: Earlier, it has been shown that the CAAP-treatment of oral squamous cell carcinoma, which is an overexpression of epidermal growth factor receptor (EGFR), led to intracellular ROS increase and a decrease of non-enzymatic antioxidants which led to the degradation and dephosphorylation of the EGFR via formation of oxidative thiol residues [21].