The top 10 differential proteins included upregulated proteins TPPP3, CRIP2, SLC9A3R2, and VAMP5 in CBF AML, and upregulated proteins MGLL, MYT1L, CAT, TESC, CLIP2, and CS in non-CBF AML. The gene discussed is VAMP5; the disease is acute myeloid leukemia.