Another compound named 3,3′,4′-trimethylellagic acid (TMEA), a tannin compound isolated from Sanguisorba officinalis L., executed its anti-cancer activity by inducing apoptosis and inhibiting angiogenesis in CRC cells via the apoptotic and VEGF/PI3K/AKT/mTOR pathways [25]. The gene discussed is AKT1; the disease is cancer.