Central obesity and low-grade inflammation (IL-6, interleukin1-receptor antagonist, CRP, and fibrinogen) were strong predictors of arterial stiffness in both sexes, while low adiponectin predicted aortic stiffness in women but not in men, suggesting a sex differences in the long-term determinants of vascular stiffness [48]. Here, ADIPOQ is linked to Abdominal obesity.