Gene associations included positive cellular response to innate immune response (interferon-alpha, interferon beta) (Ifit1, Ifit2, Stat1; FDR < 0.025) and I-kappa-B kinase/NF-kappa B signalling regulation (Stat1, Unc5cl, Tgm2; FDR < 0.005), which dysregulation of occurs in chronic inflammatory diseases and certain cancers [45]. Here, CHUK is linked to cancer.