Such claim arose from a study focusing on MNNG gastric cancer rat model whereby administration of 50, 100 or 150 mg/kg body weight of lycopene caused an increment in antioxidant enzymes as expected (SOD, CAT, GSH-Px) and increment in cytokines (IL-2, IL-4, IL-10, TNF-α) and antibodies (IgG, IgA, IgM). This evidence concerns the gene CD40LG and gastric cancer.