GPT and Hepatic fibrosis: Here, we are showing that 20 (45%) out of 44 HCV-infected asymptomatic blood donors with significant liver fibrosis (HA ≥ 34.2 ng/mL) also have normal ALT levels (<40 U/L), and this observation might have major implications for performing liver biopsies in HCV-infected persons with normal ALT serum levels.