BOK and cancer: Beroukhim et al. [81], studying genome-wide somatic copy-number alterations in a large collection of cancers, found frequent amplifications of the regions surrounding two anti-apoptotic genes, MCL1 and BCL2L1, and deletions containing two pro-apoptotic BCL2 family members, BOK and BBC3. Unfortunately, whole genome sequences of the AML patients studied here are not available to compare it.