RUNX1 and acute myeloid leukemia: Other statistically significant associations were found between the expression of gene groups and FAB type or the presence of mutations in genes recurrently mutated in AML (NPM1, RUNX1, CEBPA, DNMT3A, KRAS), genes encoding proteins interacting with the BCL2 family (ATM, EP300) and genes encoding splicing-related proteins (RBMX, HNRNPU, HNRNPH2, HNRNPUL1, SNRNP200, DDX42, DHX38, CWC27) (Table 4).