Bleomycin-induced pulmonary fibrosis was attenuated by mimics of either miR-22 or miR-16 which, when tested on TGF-β-treated lung fibroblasts in vitro, caused suppressed expression of, respectively, αSMA and CCN2 [77] or rapamycin-insensitive companion of mechanistic target of rapamycin (mTOR) (Rictor) and secreted protein acidic and rich in cysteine (Sparc) [94]. Here, TGFB1 is linked to pulmonary fibrosis.