CASP3 and glioma: Taurine upregulated gene 1 (TUG1) is a lncRNA upregulated by taurine treatment [54], and reportedly, TUG1 is downregulated in glioma tissues; this downregulation is associated with the inhibition of caspase 3/9 activation and the induction of Bcl2, which are considered to be responsible for indicators of poor prognosis in glioma patients [55].