Another study showed that the expression of lncRNA urothelial carcinoma associated 1 (UCA1) was upregulated in several glioma cell lines as compared with normal astrocytes, and that UCA1 overexpression increased the IC50 values of cisplatin and TMZ in glioma cell lines, indicating that UCA1 is associated with the promotion of chemoresistance to several antitumor agents [96]. Here, UCA1 is linked to central nervous system cancer.