EZH2 and central nervous system cancer: lncRNA Hox transcript antisense intergenic RNA (HOTAIR) is involved in cell cycle progression in U87 and LN229 glioma cell lines and intracranial xenograft tumors of nude mice due to their interaction with enhancer of zeste homolog 2 (EZH2) [38] and also acts as a ceRNA that promotes tumor progression by sponging miRNA responsible for producing tumor microenvironments [33].