NFE2L2 and neoplasm: Topical naringenin protects hairless mice from UVB-induced skin damage by inhibiting the production of SASP components (TNF-α, IL-1β, IL-6, and IL-10) and lipid hydroperoxides, while maintaining the expression of antioxidant genes, including glutathione peroxidase 1, glutathione reductase, and the nuclear factor erythroid 2-related factor 2 (Nrf2) transcription factor [117].