As shown in Table 3 (B Model 2), increased serum levels of adiponectin were associated with a higher risk of RA (OR: 1.06; per 1000 ng/mL, 95% CI: 1.01–1.12, p = 0.02) independently of other adipokines as well as inflammation markers CRP and ESR. This evidence concerns the gene ADIPOQ and rheumatoid arthritis.