MIR29B2CHG and breast carcinoma: In summary, using bioinformatics and experimental tools, we discovered the following novel findings: (1) a significant downregulation of the C1orf132 in triple-negative types of breast cancer; (2) a mouse ortholog of C1orf132 is located at a similar genomic location as its human counterpart; (3) an additional/distal promoter of C1orf132 with an enhancer effect on miR-29c generation and an inhibitory effect on cell migration; (4) RNA-seq data on distal promoter excised cells revealed many genes with altered expression involved in various cellular pathways, including mammary gland development.