G6PC1 and hydrops fetalis: Supplementation of COS 1% and 5% significantly increased the liver glycogen contents (p < 0.05 vs. NC, HF, or DF group; Figure 5) and hexokinase activity (p < 0.05 vs. NC, HF, or DF group; Figure 6A), and significantly decreased the liver glucose-6-phosphatase activity in the DF diabetic rats (p < 0.05 vs. DF group; Figure 6B).