A tumor necrosis factor alfa (TNFα) and IL1β enriched environment promotes metastasis in TNBrCa cells through the shift to a metastatic phenotype in both stromal and cancer cells, leading to an increased expression of pro-metastatic and immune-evasive chemokines, CXCL8/IL8, CCL2 and CCL5, among others, induction of angiogenesis and enhanced invasive and migration abilities of TNBrCa cells [62,122,123,124,125,126,127]. This evidence concerns the gene CXCL8 and cancer.