In order to diagnose endometriosis, Vodolazkaia et al. [34] used a biomarker model which included annexin V (a marker of apoptosis, considered as a molecule for diagnosis of minimal-mild endometriosis), vascular endothelial growth factors (VEGF), CA-125 and glycodelin/soluble intercellular-adhesion molecule-1 (sICAM-1). This evidence concerns the gene ANXA5 and endometriosis.