CCL4 and neoplasm: Some of them, including CXCL1, CXCL8, CCL2, have been described as being involved in the establishment of an inflammatory environment, promoting the development of tumor whereas CCL17, TGF-β, IL-10, MCP-1/CCL2, MIP-1β/CCL4, and MIF attract tumor-associated macrophages and regulatory T cells that inhibit cytotoxic T and NK cells [47].