Profiting from the G4-binding ability of C8, its delivery to human tumor cells (e.g., human prostate PC3 cancer cells and HeLa cervical cancer cells) was studied based on a supramolecular strategy and using different G4-forming DNA and RNA aptamers recognizing the nucleolin (NCL) that is overexpressed in the target tumor cells [180,181,182,183]. This evidence concerns the gene NUCLEOLIN and neoplasm.