AXEF showed the protective effects of NASH by decreases in intracellular fat accumulations by evidence of Oil Red O staining (Positive signals for red color, Figure 5A) as well as cell death signals including caspase 3/7 activity, BAX, BcL-xL, and BcL-2 in cellular protein levels compared with the TM group (p < 0.01 or 0.001 for Figure 5B–E,H–J). The gene discussed is BCL2; the disease is metabolic dysfunction-associated steatohepatitis.