PCDH19 and epilepsy: The disorder, which was first reported fifty years ago by Juberg and Hellman [1], represents one of the most diffuse monogenetic epileptic forms in the pediatric population [2,3,4,5], and recent molecular epidemiologic studies indicate PCDH19 as the second most clinically relevant gene in epilepsy after SCN1A [6,7,8,9].